Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length462 amino acids

Chemical FormulaC2258H3624N568O657S21

DescriptionStandard

        MSSCCWLALLALVPLAMATNPGVKVKLTEKGIEYVKKIGMASLQQKLKTMKVPDLSGTERVAPIGKVKYSLTGITIVNLGLPNSALALVPDTGICLSITNAVIMHPRDHGSFDLEVNGLTVTDSITIKSDETGRPTVSSVNCVANVGSASIKFHGGASWLYNLFSDYIDKALRSALQKQICPLVADTITDMNPHLKTLNVLAKVDKYAEVEYSMVTSPTISNASIDFSLKGEFYNIGKHQEPPFSPMPFSLPPEVNNMLYIGISAFTTNSAGFVYNNAGALSLYITDDMIPPSSPIRLNTRTFGAFIPEIAKRFPGMMIKLLVKTVKEPTIFFEPNNVTVQASGSVTAYAIQPNTTLSPLFVLNMEGSVSARLYVTGVKLAGAVTLNKIEMTLETSYVGEFQVGSLDNIFLMVLKVAVIPKVNARLEKGFPLPAIGKISLVNTQLQVLKDYMLIGTDVQFTG
    

Molecular Weight49913.70 Da

Isoelectric Point (pI)8.59

Net Charge (pH 7.0)3.91

Net Charge (pH 7.4) 3.26

Charge Density (pH 7.0) 0.0085

GRAVY Index0.23

Hydrophobic Moment 0.76

Boman Index0.18

Instability Index29.30

Aliphatic Index 102.73

Aromaticity 0.0758

Extinction Coeff. Reduced 31860.00

Extinction Coeff. Oxidized 32110.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0229302 VERIFIED: NO

Provenance & Taxonomy

OrganismSalmo trutta [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria