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MYP_042764
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Basic Information
E112
Antimicrobial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition ▸ Entry inhibitor
Antiviral ▸ Antiviral mechanism ▸ Viral fusion inhibition ▸ Fusion inhibitor
Standard
25 amino acids
C135H207N35O43
Standard
Sequence
HDWTKNITDKIDQIIHDFVDKTLPD
Physicochemical Analysis
3008.30 Da
4.86
-3.06
-3.37
-0.1223
-0.88
0.70
-0.11
11.57
89.60
0.0800
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1274.81
-10.16
42.0
42.0
99.0
213.0
6.0
26.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0155149 VERIFIED: YES
Provenance & Taxonomy
Avian leukosis virus [Virus]
Virus-derived peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Entry inhibitor Fusion inhibitor
Avian sarcoma and leukosis virus A (Virus entry); QT6
Cell-fusion assay
PaperHeptad repeat 2-based peptides inhibit avian sarcoma and leukosis virus subgroup a infection and identify a fusion intermediate. | Netter RC, Amberg SM, Balliet JW, Biscone MJ, Vermeulen A, Earp LJ, White JM, Bates P. | J Virol. 2004 | PMID:15564453 PMID15564453 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15564453/
RECORD: Rec_0169853 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 28.0%, E 0.0%, T 32.0%, C 40.0% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Antimicrobial
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/