Peptide Database

Peptide NameEC-hepcidin2

Function Ontology

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Standard StatusStandard

Sequence Length40 amino acids

Chemical FormulaC194H302N42O64S5

DescriptionStandard

        MKTFWVAVAVAVVLTCICMEESSAVPVTEVPDEEEPMSYD
    

Molecular Weight4407.04 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-7.50

Net Charge (pH 7.4) -7.76

Charge Density (pH 7.0) -0.1875

GRAVY Index0.48

Hydrophobic Moment 0.29

Boman Index0.26

Instability Index88.03

Aliphatic Index 87.50

Aromaticity 0.0750

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7115.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1653.67

LogP -12.34

H-bond Donors 57.0

H-bond Acceptors 62.0

Rotatable Bonds 137.0

Heavy Atoms 305.0

Ring Count 7.0

Amide Bonds 39.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0282266 VERIFIED: YES

Provenance & Taxonomy

OrganismNotothenia angustata [Animal]

FamilyHepcidin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

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TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)