Peptide Database

Peptide NameCycloviolacin O5

Function Ontology

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Standard StatusStandard

Sequence Length27 amino acids

Chemical FormulaC133H189N31O39S6

DescriptionStandard

        PCGESCAWFPFCFTETIGCSCQNKICY
    

Molecular Weight3038.50 Da

Isoelectric Point (pI)4.53

Net Charge (pH 7.0)-1.10

Net Charge (pH 7.4) -1.25

Charge Density (pH 7.0) -0.0406

GRAVY Index0.26

Hydrophobic Moment 0.34

Boman Index0.22

Instability Index59.56

Aliphatic Index 32.59

Aromaticity 0.1852

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1100.88

LogP -10.97

H-bond Donors 44.0

H-bond Acceptors 44.0

Rotatable Bonds 91.0

Heavy Atoms 209.0

Ring Count 8.0

Amide Bonds 28.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0237671 VERIFIED: YES

Provenance & Taxonomy

OrganismViola tricolor [Plant]

FamilyCyclotide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

-

TargetEscherichia coli TOP10

MethodMex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)