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MYP_042751
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Basic Information
Gastric inhibitory polypeptide
Hormonal / Endocrine ▸ Hormone peptide
Metabolic
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Reproductive biology ▸ Reproductive modulation
Standard
42 amino acids
C226H338N60O66S
Standard
Sequence
YAEGTFISDYSIAMDKIHQQDFVNWLLAQKGKKNDWKHNITQ
Physicochemical Analysis
4983.53 Da
6.92
-0.07
-0.38
-0.0016
-0.80
0.36
-0.05
33.32
69.76
0.1429
13980.00
13980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
2084.97
-18.11
70.0
69.0
168.0
353.0
10.0
48.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0014593 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Glucagon
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone Metabolic
PMID6745415 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/6745415/
RECORD: Rec_0110243 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Hormone
RECORD: Rec_0175958 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
GIP
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Insulin secretion stimulation Glucose clearance
0.0218±0.0015 μM
EC50
Human plasma, in vitro; 21600 s
PMID15246869 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15246869/
RECORD: Rec_0244381 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 35.7%, E 0.0%, T 28.6%, C 35.7% [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication
PaperNeuroPedia: neuropeptide database and spectral library PMID21821666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21821666/
RECORD: Rec_0244533 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
GIP
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antihyperglycemic Metabolic regulation
MS
P800 plasma, in vitro; >345600 s
PaperDegradation and Stabilization of Peptide Hormones in Human Blood Specimens PMID26222180 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/26222180/
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