Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length188 amino acids

Chemical FormulaC955H1444N212O284S10

DescriptionStandard

        IDDLAEIDYSLSSLPAVFQPFIDLDLKGTVFPAGNYIGSPYVVAPFSVTDQSDSMLLLAFSEYYFQTSSFAYYTAGAFNMTIAEEVIFCSTRSGFLYFFLFFCPAISQVAKYSVTPYPVMLKLMATEIPVISLEQDSFTVEIQGSMEVLAVLPDSTTQSLFTMNVAANSSISLNIFDQKLMGSLCLNR
    

Molecular Weight20759.58 Da

Isoelectric Point (pI)4.05

Net Charge (pH 7.0)-12.25

Net Charge (pH 7.4) -12.54

Charge Density (pH 7.0) -0.0652

GRAVY Index0.47

Hydrophobic Moment 0.52

Boman Index0.28

Instability Index48.86

Aliphatic Index 95.96

Aromaticity 0.1436

Extinction Coeff. Reduced 14900.00

Extinction Coeff. Oxidized 15025.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 7830.01

LogP -85.30

H-bond Donors 269.0

H-bond Acceptors 282.0

Rotatable Bonds 660.0

Heavy Atoms 1461.0

Ring Count 37.0

Amide Bonds 201.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0149017 VERIFIED: NO

Provenance & Taxonomy

OrganismMionectes macconnelli [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria