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MYP_042721
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Basic Information
P4, Longicin (53-73)
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antifungal
Antiparasitic ▸ Antiprotozoal
Antiparasitic ▸ Antiprotozoal ▸ Anti-Toxoplasma
Antiparasitic ▸ General antiparasitic ▸ Antiparasitic
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
21 amino acids
C96H160N32O28S3
Standard
Sequence
SIGRRGGYCAGIIKQTCTCYR
Physicochemical Analysis
2306.69 Da
9.50
3.43
3.17
0.1632
-0.21
0.48
-0.10
45.23
60.48
0.0952
2980.00
3105.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1001.28
-12.60
41.0
35.0
76.0
159.0
2.0
21.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0254787 VERIFIED: YES
Provenance & Taxonomy
Haemaphysalis longicornis [Animal]
Longicin
44386
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiparasitic Anti-Babesia
Babesia bigemina Argentine
Microscopy (Giemsa staining)
PMID22102016 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22102016/
RECORD: Rec_0257413 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Escherichia coli O157:H7 ATCC 35150
2 μM
MIC
PMID19940394;23553969 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19940394/
RECORD: Rec_0275172 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiparasitic Defensin-Like Peptide
PaperParaPep: a web resource for experimentally validated antiparasitic peptide sequences and their structures PMID24923818 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24923818/
RECORD: Rec_0406895 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Pseudomonas aeruginosa ATCC 10145
15 μg/mL
MBC
PMID19940394;23553969 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19940394/
RECORD: Rec_0419350 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Defensin
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antiparasitic Antiprotozoal Antifungal
Escherichia coli ATCC 700928
7.5 μg/mL
MBC
PMID19940394;23553969 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/19940394/
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