Peptide Database

Peptide NameBeta-defensin 12

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length75 amino acids

Chemical FormulaC353H578N102O93S9

DescriptionStandard

        MAGKRMLWFAAFLILLAVPGNAQGSKHVCRTAGGQCRMGICLSGEVRIGDCFIPVILCCKKYPVRKETGELQGGA
    

Molecular Weight8027.58 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)5.53

Net Charge (pH 7.4) 5.16

Charge Density (pH 7.0) 0.0738

GRAVY Index0.32

Hydrophobic Moment 0.59

Boman Index0.14

Instability Index34.65

Aliphatic Index 91.07

Aromaticity 0.0667

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7365.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3097.13

LogP -27.64

H-bond Donors 114.0

H-bond Acceptors 109.0

Rotatable Bonds 268.0

Heavy Atoms 557.0

Ring Count 10.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0010582 VERIFIED: NO

Provenance & Taxonomy

OrganismCrocodylus porosus [Animal]

FamilyDefensin

Tax ID8502

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal