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MYP_042707
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Basic Information
Fallaxidin 3.1
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Standard
16 amino acids
C76H134N20O20
Standard
Sequence
GLLDLAKHVIGIASKL
Physicochemical Analysis
1648.00 Da
8.60
0.85
0.59
0.0529
0.99
0.50
0.36
-1.24
176.88
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
638.07
-3.40
22.0
22.0
57.0
116.0
1.0
15.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0050388 VERIFIED: NO
Provenance & Taxonomy
Eastern dwarf [Animal]
33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0128607 VERIFIED: YES
Provenance & Taxonomy
Litoria fallax [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
RECORD: Rec_0155468 VERIFIED: YES
Provenance & Taxonomy
Litoria fallax [Animal]
Fallaxidin
Structure & Mods
ribosomal mature linear peptide [Linear]
Gene-encoded natural peptide composed of standard L-amino acids [L]
Bio-Activity Profile
Antimicrobial Antibacterial
PaperR.J. Jackway et al. / Rapid Communications in Mass Spectrometry 22 (2008) 3207-3216. The fallaxidin peptides from the skin secretion of the eastern dwarf tree frog Litoria fallax. Sequence determination by positive and negative ion electrospray mass spectrometry: antimicrobial activity and cDNA cloning of the fallaxidins Evidence URLhttps://www.uniprot.org/uniprotkb/B5LUQ8/entry
RECORD: Rec_0171646 VERIFIED: YES
Provenance & Taxonomy
Eastern dwarf tree [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperThe fallaxidin peptides from the skin secretion of the Eastern Dwarf Tree Frog Litoria fallax. Sequence determination by positive and negative ion electrospray mass spectrometry: antimicrobial activity and cDNA cloning of the fallaxidins.
RECORD: Rec_0179454 VERIFIED: YES
Provenance & Taxonomy
Litoria fallax [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Enterococcus faecalis
100 μM
MIC
PMID18803332 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/18803332/
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