Peptide Database

Peptide NameSLAY-screened peptide P2938

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC117H178N34O28S

DescriptionStandard

        CYYPEYRRIASRHALYLIPR
    

Molecular Weight2540.94 Da

Isoelectric Point (pI)9.62

Net Charge (pH 7.0)2.84

Net Charge (pH 7.4) 2.56

Charge Density (pH 7.0) 0.1418

GRAVY Index-0.56

Hydrophobic Moment 0.56

Boman Index-0.19

Instability Index64.77

Aliphatic Index 88.00

Aromaticity 0.2000

Extinction Coeff. Reduced 5960.00

Extinction Coeff. Oxidized 5960.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1013.37

LogP -5.55

H-bond Donors 39.0

H-bond Acceptors 33.0

Rotatable Bonds 76.0

Heavy Atoms 180.0

Ring Count 7.0

Amide Bonds 19.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0298573 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/