Peptide Database

Peptide NameEndolysin (EC 4.2.2.n2) (Lysis protein) (Lysozyme) (Transglycosylase)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Bacteriolytic activity ▸ Bacteriolytic enzyme

Enzyme / Catalytic activity ▸ Lyase

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length154 amino acids

Chemical FormulaC749H1193N211O219S6

DescriptionStandard

        MAISKNMKAFLDMLAYSEGTDNGRQKTNNHGYDVIVGGSLFTDYSGHPRKLISLPKLGIKSTAAGRYQVLAKFYDAYKKQLRLPDFSPASQDAIAMQLILECKATADIEAGRIADAIHKCRSRWASLPGAGYGQHEQKLDKLIQVYKNAGGVVA
    

Molecular Weight16850.16 Da

Isoelectric Point (pI)9.42

Net Charge (pH 7.0)6.83

Net Charge (pH 7.4) 6.34

Charge Density (pH 7.0) 0.0443

GRAVY Index-0.31

Hydrophobic Moment 0.68

Boman Index-0.00

Instability Index35.02

Aliphatic Index 84.42

Aromaticity 0.0844

Extinction Coeff. Reduced 17420.00

Extinction Coeff. Oxidized 17545.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6947.42

LogP -69.44

H-bond Donors 242.0

H-bond Acceptors 236.0

Rotatable Bonds 569.0

Heavy Atoms 1185.0

Ring Count 23.0

Amide Bonds 166.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0418702 VERIFIED: NO

Provenance & Taxonomy

OrganismShigella phage Sf11 SMD-2017 [Virus]

FamilyGlycosyl hydrolase 24

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Bacteriolytic enzyme Lyase Cytolytic Non-hemolytic