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MYP_042527
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Basic Information
Unnamed
Antimicrobial
Antiviral
Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition ▸ Replication inhibitor
Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition
Standard
33 amino acids
C164H246N44O47S
Standard
Sequence
GELGRLVYLLDGPGYDPIHCDVVTRGGSHLFNF
Physicochemical Analysis
3618.04 Da
5.26
-2.07
-2.40
-0.0628
0.05
0.60
0.18
13.35
97.27
0.1212
2980.00
2980.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1431.31
-11.74
50.0
48.0
112.0
256.0
8.0
33.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0113111 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antimicrobial Antiviral
PaperAVPdb: a database of experimentally validated antiviral peptides targeting medically important viruses PMID24285301 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24285301/
RECORD: Rec_0142980 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antiviral Protease inhibitor Replication inhibitor
Hepatitis C virus (Replication); Escherichia coli
0.0113 μM
FRET assay
PaperHigh affinity peptide inhibitors of the hepatitis C virus NS3-4A protease refractory to common resistant mutants. | Kugler J, Schmelz S, Gentzsch J, Haid S, Pollmann E, van den Heuvel J, Franke R, Pietschmann T, Heinz DW, Collins J. | J Biol Chem. 2012 | PMID:22965230 PMID22965230 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/22965230/