Peptide Database

Peptide NameMaximins 6 Hv [Cleaved into: Maximin-6

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Antimicrobial ▸ Antifungal ▸ Anti-Candida

Antimicrobial ▸ Antifungal ▸ Fungicidal activity

Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytolysis / cell lysis ▸ Cytolytic activity

Standard StatusStandard

Sequence Length144 amino acids

Chemical FormulaC691H1140N200O212S3

DescriptionStandard

        MNFKYIVAVSFLIASGYARSEENDVQSLSQREVLEEETLREIRGIGGALLSAGKSALKGLAKGLAEHFANGKRTAKGHEVMKRLEAVMRDLDSLDHPEEASERETRGFNQEEIANLFTKKEKRILGPVLSLVGSALGGLIKKIG
    

Molecular Weight15737.85 Da

Isoelectric Point (pI)7.97

Net Charge (pH 7.0)0.80

Net Charge (pH 7.4) 0.38

Charge Density (pH 7.0) 0.0056

GRAVY Index-0.30

Hydrophobic Moment 0.65

Boman Index-0.04

Instability Index37.62

Aliphatic Index 96.25

Aromaticity 0.0486

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 6696.25

LogP -67.41

H-bond Donors 234.0

H-bond Acceptors 219.0

Rotatable Bonds 555.0

Heavy Atoms 1106.0

Ring Count 12.0

Amide Bonds 151.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0011836 VERIFIED: NO

Provenance & Taxonomy

OrganismBombina maxima [Animal]

FamilyBombinin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Amphibian defense peptide Antibiotic Antimicrobial Antifungal Fungicide Anti-Candida Cytolytic Hemolytic Non-ribosomal

MethodQualitative functional evidence

RECORD: Rec_0363746 VERIFIED: NO