Peptide Database

Peptide NamePaneth cell-specific alpha-defensin 25

Function Ontology

Antimicrobial

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length98 amino acids

Chemical FormulaC473H738N138O141S8

DescriptionStandard

        MRTLALLAALLLLAFHAQAQPLGENDDQVPAQDQPGAEVQGMTISFEGDERSTRDASGSRSALICHCSFSCRSPYKKIGYCHLRRLHFCCPSWLNFVD
    

Molecular Weight10870.28 Da

Isoelectric Point (pI)6.39

Net Charge (pH 7.0)-1.19

Net Charge (pH 7.4) -1.72

Charge Density (pH 7.0) -0.0122

GRAVY Index-0.16

Hydrophobic Moment 0.56

Boman Index0.01

Instability Index53.28

Aliphatic Index 78.78

Aromaticity 0.0816

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 4458.86

LogP -47.79

H-bond Donors 160.0

H-bond Acceptors 152.0

Rotatable Bonds 353.0

Heavy Atoms 760.0

Ring Count 18.0

Amide Bonds 105.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0021403 VERIFIED: YES

Provenance & Taxonomy

OrganismEquus caballus [Animal]

FamilyDefensin

Tax ID9796

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Defensin Non-hemolytic Non-ribosomal