Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length74 amino acids

Chemical FormulaC383H606N104O111S8

DescriptionStandard

        MKILGIFLTFVFTVSCGPSVSQKKTREKTREITERKTECYLVRGACKTSCNTWEYIYNYCNNEPCCVVREYIRP
    

Molecular Weight8700.06 Da

Isoelectric Point (pI)8.92

Net Charge (pH 7.0)4.44

Net Charge (pH 7.4) 4.09

Charge Density (pH 7.0) 0.0600

GRAVY Index-0.35

Hydrophobic Moment 0.61

Boman Index-0.10

Instability Index43.24

Aliphatic Index 67.03

Aromaticity 0.1216

Extinction Coeff. Reduced 12950.00

Extinction Coeff. Oxidized 13325.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3525.02

LogP -33.83

H-bond Donors 133.0

H-bond Acceptors 124.0

Rotatable Bonds 286.0

Heavy Atoms 606.0

Ring Count 13.0

Amide Bonds 78.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0063880 VERIFIED: NO

Provenance & Taxonomy

OrganismMyotis lucifugus [Animal]

FamilyDefensin

Tax ID59463

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence