Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length81 amino acids

Chemical FormulaC385H632N116O109S10

DescriptionStandard

        MSTPTVLSLNVASILSHKSFRSVLACCIATSSKVHYIGFKAAEICATCRLGRGKCRKKCQHDEIVFGTCKHDTFCCRPRVE
    

Molecular Weight8950.50 Da

Isoelectric Point (pI)9.25

Net Charge (pH 7.0)7.77

Net Charge (pH 7.4) 7.20

Charge Density (pH 7.0) 0.0959

GRAVY Index0.06

Hydrophobic Moment 0.55

Boman Index-0.02

Instability Index37.10

Aliphatic Index 77.04

Aromaticity 0.0617

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3618.13

LogP -40.47

H-bond Donors 140.0

H-bond Acceptors 131.0

Rotatable Bonds 299.0

Heavy Atoms 620.0

Ring Count 11.0

Amide Bonds 82.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0125230 VERIFIED: NO

Provenance & Taxonomy

OrganismMonodelphis domestica [Bacterium]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Defensin Non-hemolytic Non-ribosomal