Peptide Database

Peptide NameProstate Specific Antigen (Prodrug 2)

Function Ontology

Anticancer

Anticancer ▸ Prostate cancer targeting

Delivery / Targeting ▸ Targeting ligand ▸ Prostate cancer targeting

Standard StatusStandard

Sequence Length6 amino acids

Chemical FormulaC29H50N10O10

DescriptionStandard

        HSSKLQ
    

Molecular Weight698.77 Da

Isoelectric Point (pI)8.76

Net Charge (pH 7.0)0.85

Net Charge (pH 7.4) 0.59

Charge Density (pH 7.0) 0.1411

GRAVY Index-1.40

Hydrophobic Moment 0.24

Boman Index-0.34

Instability Index80.62

Aliphatic Index 65.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 347.07

LogP -4.79

H-bond Donors 12.0

H-bond Acceptors 12.0

Rotatable Bonds 24.0

Heavy Atoms 49.0

Ring Count 1.0

Amide Bonds 6.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0006894 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermMu (Morpholino)

C-TermCyclopamine

Bio-Activity Profile

Function

Anticancer Prostate cancer targeting

MethodHydrolysis and RP-HPLC

Half-Lifein vitro; 79200 s

RECORD: Rec_0071294 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermSuccinylation

C-TermAmidation

Bio-Activity Profile

Function

Anticancer

Activity0.0093±0.00026 μM

MethodHPLC

Half-LifeConjuagte 2+PSA(Prostate-specific antigen), in vitro; 43200 s