Peptide Database

Peptide NameKiller protein of pyocin s3

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length487 amino acids

Chemical FormulaC2401H3747N673O721S16

DescriptionStandard

        TCPCRARLINSVMDSYEKQEEPADRAVAPTNMAAQNFSSPVKAAGSIQPGPPPVTQAPPPPIPVFTKSCQRGKGCTDAGTEAEPADNFGRMAVYQVPSSSALVTAQKPEPPPQGKKHPPEPDKPQDKKLPWYKRWFGGGKEKVEAAATAVAATTRSVAADGEALVMRYIGGSAISSGRWLAAPNPLTVGLMGLFYSPRLNEGEEDYLNRYRLSEIAEQFGKAPTRVRFRWIRDEKSGRMTIQGYHVSPESGLDKVPVRMMTLNRTTGNYEFWEPGEHRPTILWTPNEQEFQVPAHTGNEERPFIPSQITVLPIPEKVGSDIESLPMPEEKDFRDYILILPIPNMPPVYVYLSKPPVKPLEVGEYHDLAGRSRNDGMDIDHIPSQGALRKYLVNKYGHRLSGDQLEATLRKGAAMAIPKQVHQKYSETYGGRNSATKKTQDAFDLKAAVDSNFNAQLPALRENGYTDEQLNKALEKLHQLNKEQGWYE
    

Molecular Weight54089.55 Da

Isoelectric Point (pI)7.62

Net Charge (pH 7.0)1.23

Net Charge (pH 7.4) 0.37

Charge Density (pH 7.0) 0.0025

GRAVY Index-0.68

Hydrophobic Moment 0.67

Boman Index-0.08

Instability Index50.94

Aliphatic Index 66.55

Aromaticity 0.0801

Extinction Coeff. Reduced 66810.00

Extinction Coeff. Oxidized 67060.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0145986 VERIFIED: YES

Provenance & Taxonomy

OrganismPhotorhabdus khanii subsp. guanajuatensis [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Anti-Gram-negative Antibiotic Bacteriocin Non-hemolytic Non-ribosomal

TargetEscherichia coli (Gram-negative)

PaperPhotorhabdus khanii subsp. guanajuatensis subsp. nov., isolated from Heterorhabditis atacamensis, and Photorhabdus luminescens subsp. mexicana subsp. nov., isolated from Heterorhabditis mexicana entomopathogenic nematodes PMID30688647 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/30688647/