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MYP_042331
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Basic Information
Cecropin B
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antifungal
Standard
36 amino acids
C178H304N52O43S
Standard
Sequence
KWKVFKKIEKMGRNIRNGIVKAGPAIAVLGEAKALG
Physicochemical Analysis
3892.71 Da
10.73
6.76
6.54
0.1877
-0.08
0.89
0.01
34.72
103.06
0.0556
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1555.54
-11.00
54.0
51.0
138.0
274.0
4.0
37.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0017104 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
S. cerevisiae spp
3.1 μM
IC50
PMID23326415 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23326415/
RECORD: Rec_0020800 VERIFIED: NO
Provenance & Taxonomy
Bombyx mori [Animal]
7091
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
PaperPatent US 6872705 B2 Evidence URLhttps://patents.google.com/patent/US6872705B2/en PatentUS 6872705 B2
RECORD: Rec_0022486 VERIFIED: YES
Provenance & Taxonomy
Hyalophora cecropia [Animal]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative
PMID7019715 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/7019715/
RECORD: Rec_0062452 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Cecropin
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Antifungal
B. cinerea 101
25 μM
IC50
PMID23326415 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23326415/
RECORD: Rec_0100772 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Cecropin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
-
Escherichia coli TOP10
Mex pooled growth assay (OD_ID at 4.5 h; Wald adjusted p-value)
PaperKoch P, Schmitt S, Cardner M, Beerenwinkel N, Panke S, Held M. Discovery of antimicrobials by massively parallelized growth assays (Mex). Scientific Reports. 2022;12:4097. doi:10.1038/s41598-022-07755-7 PMID35260685 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/35260685/
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