Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length183 amino acids

Chemical FormulaC910H1451N253O254S9

DescriptionStandard

        AQEPMAHEPMLLLAVTEFVANSAASTYFTAGALHKNISSDMLPRRFPLQLRTKSMEVFSPQLQERYPDQPMELHLWARQQPLLSCRPDALHGTLFSSAEAFVVLPNATRVPAFLLNIDANVTGKPTITRNRLRGTVSLRGSVPNPELGLPVPQVKRLETLLKFGLWLFGVPRANSECCLCPVS
    

Molecular Weight20288.38 Da

Isoelectric Point (pI)9.10

Net Charge (pH 7.0)4.13

Net Charge (pH 7.4) 3.65

Charge Density (pH 7.0) 0.0226

GRAVY Index-0.03

Hydrophobic Moment 0.57

Boman Index0.06

Instability Index59.03

Aliphatic Index 93.28

Aromaticity 0.0710

Extinction Coeff. Reduced 13980.00

Extinction Coeff. Oxidized 14230.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 8020.02

LogP -92.49

H-bond Donors 276.0

H-bond Acceptors 271.0

Rotatable Bonds 647.0

Heavy Atoms 1426.0

Ring Count 37.0

Amide Bonds 198.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0276308 VERIFIED: NO

Provenance & Taxonomy

OrganismClimacteris rufus [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria