Peptide Database

Peptide NameProgonadoliberin-3

Function Ontology

Hormonal / Endocrine ▸ Hormone peptide

Reproductive biology ▸ Reproductive modulation

Standard StatusStandard

Sequence Length66 amino acids

Chemical FormulaC337H515N99O98S2

DescriptionStandard

        QHWSYGWLPGGKRSVGELEATIRMMGTGGVVSLPEETSAQTQERLRPYNIINDGGYFNRKKRFFHE
    

Molecular Weight7585.43 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)1.95

Net Charge (pH 7.4) 1.62

Charge Density (pH 7.0) 0.0296

GRAVY Index-0.81

Hydrophobic Moment 0.54

Boman Index-0.10

Instability Index53.68

Aliphatic Index 57.58

Aromaticity 0.1212

Extinction Coeff. Reduced 15470.00

Extinction Coeff. Oxidized 15470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3209.02

LogP -32.55

H-bond Donors 113.0

H-bond Acceptors 104.0

Rotatable Bonds 250.0

Heavy Atoms 536.0

Ring Count 15.0

Amide Bonds 71.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0082726 VERIFIED: YES

Provenance & Taxonomy

OrganismPorichthys notatus [Animal]

FamilyProgonadoliberin

Tax ID45384

Structure & Mods

Configlinear peptide [Linear]

Chiralitynoncanonical stereochemical modification [Modified]

N-TermPyroglutamate

Other Mods10:Glycine amide

Bio-Activity Profile

Function

Hormone Endocrine Reproductive regulator

Half-LifeMammalian: 0.8 hour; Yeast: 10 min; E. coli: >10 hour