Peptide Database

Peptide NameColicin-E7 (EC 3.1.-.-)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Enzyme / Catalytic activity ▸ Hydrolase

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length56 amino acids

Chemical FormulaC272H437N93O78S

DescriptionStandard

        MREGKAPKARYRDRAGKRGSFELHHADEVAKGGKVYDVDNLNVVTPKHHIGIHRNG
    

Molecular Weight6290.02 Da

Isoelectric Point (pI)9.99

Net Charge (pH 7.0)4.94

Net Charge (pH 7.4) 4.45

Charge Density (pH 7.0) 0.0882

GRAVY Index-1.07

Hydrophobic Moment 0.56

Boman Index-0.27

Instability Index10.35

Aliphatic Index 62.68

Aromaticity 0.0536

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2788.45

LogP -30.37

H-bond Donors 98.0

H-bond Acceptors 89.0

Rotatable Bonds 214.0

Heavy Atoms 444.0

Ring Count 10.0

Amide Bonds 58.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0321639 VERIFIED: NO

Provenance & Taxonomy

OrganismPseudomonas frederiksbergensis [Bacterium]

FamilyPyocin

Structure & Mods

Configlinear polypeptide/propeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Bacteriocin Hydrolase Non-hemolytic Non-ribosomal