Peptide Database

Peptide NameBeta-defensin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length72 amino acids

Chemical FormulaC352H585N107O102S7

DescriptionStandard

        MRIPVLLLAISLLLSQDPPVRSEFEVDRICGYGTARCRRKCQSQEYRIGRCPSTSACCLKKWSSSLLQSTKH
    

Molecular Weight8172.52 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)6.53

Net Charge (pH 7.4) 6.16

Charge Density (pH 7.0) 0.0907

GRAVY Index-0.24

Hydrophobic Moment 0.55

Boman Index-0.13

Instability Index68.84

Aliphatic Index 86.67

Aromaticity 0.0556

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3400.32

LogP -37.18

H-bond Donors 129.0

H-bond Acceptors 117.0

Rotatable Bonds 273.0

Heavy Atoms 568.0

Ring Count 10.0

Amide Bonds 75.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0409828 VERIFIED: NO

Provenance & Taxonomy

OrganismProlemur simus [Animal]

FamilyDefensin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Defensin Non-hemolytic Non-ribosomal

MethodQualitative functional evidence