Peptide Database

Peptide NameKunitz-type trypsin inhibitor IVTI

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Antimicrobial ▸ Antifungal

Enzyme modulation ▸ Enzyme inhibition ▸ Protease inhibition

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length29 amino acids

Chemical FormulaC128H202N34O44S

DescriptionStandard

        EVVLDSDGEMLRNGGKYYLSPASPIGGGA
    

Molecular Weight2953.24 Da

Isoelectric Point (pI)4.32

Net Charge (pH 7.0)-2.16

Net Charge (pH 7.4) -2.34

Charge Density (pH 7.0) -0.0745

GRAVY Index-0.23

Hydrophobic Moment 0.58

Boman Index0.12

Instability Index67.52

Aliphatic Index 80.69

Aromaticity 0.0690

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1241.90

LogP -14.12

H-bond Donors 42.0

H-bond Acceptors 43.0

Rotatable Bonds 95.0

Heavy Atoms 207.0

Ring Count 4.0

Amide Bonds 29.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0027810 VERIFIED: NO

Provenance & Taxonomy

OrganismInga vera [other]

FamilyProtease inhibitor I3 (leguminous Kunitz-type inhibitor)

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antimicrobial Antibiotic Antifungal Protease inhibitor Serine protease inhibitor Cytotoxic Enzyme Inhibitor Non-hemolytic

TargetNo Target Organism Found