Peptide Database

Peptide NameCecropin-A1

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length63 amino acids

Chemical FormulaC307H501N87O83S

DescriptionStandard

        MKFYNIFVFVALILAITIGQSEAGWLKKIGKKIERVGQHTRDATIQGLGVAQQAANVAATARG
    

Molecular Weight6770.86 Da

Isoelectric Point (pI)10.28

Net Charge (pH 7.0)4.59

Net Charge (pH 7.4) 4.31

Charge Density (pH 7.0) 0.0728

GRAVY Index0.26

Hydrophobic Moment 0.94

Boman Index0.16

Instability Index39.75

Aliphatic Index 106.98

Aromaticity 0.0794

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 2762.70

LogP -24.79

H-bond Donors 96.0

H-bond Acceptors 90.0

Rotatable Bonds 231.0

Heavy Atoms 478.0

Ring Count 7.0

Amide Bonds 69.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0140696 VERIFIED: NO

Provenance & Taxonomy

OrganismDrosophila mauritiana [Animal]

FamilyCecropin

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Anti-Gram-positive Non-hemolytic Non-ribosomal

TargetGram-negative bacteria; Gram-positive bacteria

MethodQualitative functional evidence