Peptide Database

Peptide NameNatriuretic peptide CnNP-b

Function Ontology

Cardiovascular

Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide

Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity

Hormonal / Endocrine ▸ Hormone peptide

Regulatory peptide ▸ Biological modulation

Regulatory peptide ▸ Biological regulation

Standard StatusStandard

Sequence Length34 amino acids

Chemical FormulaC135H227N43O46S3

DescriptionStandard

        SGSKTATKGDGCFGVRIDRIGSTSGMGCGGVPKP
    

Molecular Weight3284.70 Da

Isoelectric Point (pI)9.38

Net Charge (pH 7.0)2.44

Net Charge (pH 7.4) 2.20

Charge Density (pH 7.0) 0.0718

GRAVY Index-0.32

Hydrophobic Moment 0.54

Boman Index0.01

Instability Index12.07

Aliphatic Index 42.94

Aromaticity 0.0294

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1424.11

LogP -22.65

H-bond Donors 53.0

H-bond Acceptors 52.0

Rotatable Bonds 109.0

Heavy Atoms 227.0

Ring Count 3.0

Amide Bonds 33.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0301003 VERIFIED: YES

Provenance & Taxonomy

OrganismCryptophis nigrescens [Animal]

FamilyNatriuretic peptide CnNP

Tax ID292442

Structure & Mods

Configdisulfide-constrained peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide12-28

Bio-Activity Profile

Function

Hormone Endocrine Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Receptor modulation

Half-LifeMammalian: 1.9 hour; Yeast: >20 hour; E. coli: >10 hour