Peptide Database

Peptide NameUnnamed

Function Ontology

Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive

Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory

Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory

Metabolic ▸ Glucose metabolism ▸ Antidiabetic

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid antagonist

Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid receptor ligand

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Other / Curated residual function label ▸ Generic enzyme inhibition annotation

Standard StatusStandard

Sequence Length4 amino acids

Chemical FormulaC32H36N4O8

DescriptionStandard

        YPYY
    

Molecular Weight604.65 Da

Isoelectric Point (pI)5.52

Net Charge (pH 7.0)-0.24

Net Charge (pH 7.4) -0.45

Charge Density (pH 7.0) -0.0607

GRAVY Index-1.38

Hydrophobic Moment 0.06

Boman Index0.23

Instability Index69.20

Aliphatic Index 0.00

Aromaticity 0.7500

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4470.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 202.52

LogP 1.20

H-bond Donors 7.0

H-bond Acceptors 8.0

Rotatable Bonds 12.0

Heavy Atoms 44.0

Ring Count 4.0

Amide Bonds 3.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0425554 VERIFIED: YES

Provenance & Taxonomy

OrganismBos taurus [Animal]

Tax ID9913

Structure & Mods

Configproteolytic peptide fragment [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antihypertensive ACE inhibitory

TargetAngiotensin-converting enzyme (ACE)

Activity90.9 μM

MethodIC50

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