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MYP_042193
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Basic Information
Unnamed
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Enzyme modulation ▸ Enzyme inhibition ▸ DPP-IV inhibition ▸ DPP-IV inhibitory
Metabolic ▸ Glucose metabolism ▸ Antidiabetic
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid antagonist
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Opioid receptor ligand
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Standard
4 amino acids
C32H36N4O8
Standard
Sequence
YPYY
Physicochemical Analysis
604.65 Da
5.52
-0.24
-0.45
-0.0607
-1.38
0.06
0.23
69.20
0.00
0.7500
4470.00
4470.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
202.52
1.20
7.0
8.0
12.0
44.0
4.0
3.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0267498 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Casoxin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Opioid Antagonist
opioid receptor
PaperChiba H., Yoshikawa M.. Biologically active peptides from food proteins: new opioid peptides from milk proteins. in ?Protein tailoring for food and medical uses¡±, ed. Feeney R. E., Whitaker J. R., Marcel Dekker, New York, 123-153, 1986.
RECORD: Rec_0274598 VERIFIED: YES
Provenance & Taxonomy
Bos taurus [Animal]
9913
Structure & Mods
proteolytic peptide fragment [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Spontaneously hypertensive rats (SHR)
90.9 μM
IC50
PaperAntihypertensive effect of bioactive peptides produced by protease-facilitated lactic acid fermentation of Milk
RECORD: Rec_0284563 VERIFIED: YES
Provenance & Taxonomy
Jatropha curcas [Plant]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
90.9 μM
IC50
PaperEffect of Jatropha curcas Peptide Fractions on the Angiotensin I-Converting Enzyme Inhibitory Activity PMID24224169 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24224169/
RECORD: Rec_0370416 VERIFIED: NO
Provenance & Taxonomy
Bos taurus [Animal]; Homo sapiens [Animal]
Casein-derived peptide
9913, 9606
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Neuropeptide Enzyme inhibitory
myenteric plexus of guinea pig ileum longitudianal muscle
RECORD: Rec_0396403 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
4.05 pIC50
pIC50
PaperWhat are the ideal properties for functional food peptides with antihypertensive effect? A computational peptidology approach. PMID23871047 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23871047/
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