Peptide Database

Peptide NameLantibiotic

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC143H212N40O50S5

DescriptionStandard

        AATQAADSGGVFCTISHECHYNSVSPSSWMTCC
    

Molecular Weight3451.78 Da

Isoelectric Point (pI)5.15

Net Charge (pH 7.0)-2.07

Net Charge (pH 7.4) -2.42

Charge Density (pH 7.0) -0.0626

GRAVY Index0.09

Hydrophobic Moment 0.28

Boman Index0.18

Instability Index92.09

Aliphatic Index 41.52

Aromaticity 0.0909

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 7240.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1421.96

LogP -20.99

H-bond Donors 54.0

H-bond Acceptors 55.0

Rotatable Bonds 104.0

Heavy Atoms 238.0

Ring Count 7.0

Amide Bonds 34.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0137581 VERIFIED: NO

Provenance & Taxonomy

OrganismBacillus thuringiensis [Bacterium]

FamilyLantibiotic

Structure & Mods

Configlinear lantibiotic precursor [Linear]

Chiralitypost-translationally modified ribosomal peptide [Modified]

Other ModsLantibiotic-family precursor annotation suggests post-translational lanthionine/methyllanthionine thioether crosslinks in the mature peptide

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Lantibiotic Anti-Gram-positive Non-hemolytic

TargetGram-positive bacteria

MethodQualitative functional evidence