Peptide Database

Peptide NamePotassium channel toxin alpha-KTx 17.1

Function Ontology

Membrane / Ion-channel modulation ▸ Ion channel inhibition

Membrane / Ion-channel modulation ▸ Potassium channel modulation ▸ Potassium channel inhibitor

Venom / Toxin ▸ General toxin ▸ Toxin

Venom / Toxin ▸ Toxin

Standard StatusStandard

Sequence Length30 amino acids

Chemical FormulaC140H220N42O50S6

DescriptionStandard

        QTQCQSVRDCQQYCLTPDRCSYGTCYCKTT
    

Molecular Weight3483.89 Da

Isoelectric Point (pI)7.76

Net Charge (pH 7.0)0.70

Net Charge (pH 7.4) 0.40

Charge Density (pH 7.0) 0.0233

GRAVY Index-0.85

Hydrophobic Moment 0.47

Boman Index-0.27

Instability Index13.90

Aliphatic Index 22.67

Aromaticity 0.1000

Extinction Coeff. Reduced 4470.00

Extinction Coeff. Oxidized 4845.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1540.60

LogP -22.46

H-bond Donors 60.0

H-bond Acceptors 57.0

Rotatable Bonds 111.0

Heavy Atoms 238.0

Ring Count 4.0

Amide Bonds 34.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0356883 VERIFIED: YES

Provenance & Taxonomy

OrganismMesobuthus martensii [Animal]

FamilyPotassium channel inhibitor family

Tax ID34649; 0

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermPyroglutamate

C-TermAmidation

Disulfide4-20; 10-25; 14-27

Bio-Activity Profile

Function

Toxin Venom Potassium channel inhibitor family