Peptide Database

Peptide NameSLAY-screened peptide P907

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC112H163N23O26S2

DescriptionStandard

        CTSYPFLMPLQFLPLGQAWV
    

Molecular Weight2311.76 Da

Isoelectric Point (pI)5.52

Net Charge (pH 7.0)-0.25

Net Charge (pH 7.4) -0.47

Charge Density (pH 7.0) -0.0125

GRAVY Index0.77

Hydrophobic Moment 0.23

Boman Index0.46

Instability Index81.48

Aliphatic Index 97.50

Aromaticity 0.2000

Extinction Coeff. Reduced 6990.00

Extinction Coeff. Oxidized 6990.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 752.51

LogP -1.64

H-bond Donors 25.0

H-bond Acceptors 28.0

Rotatable Bonds 65.0

Heavy Atoms 163.0

Ring Count 8.0

Amide Bonds 21.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0180741 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/