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MYP_042090
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Basic Information
Caerin-2.2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Antibiotic activity
Enzyme modulation ▸ Enzyme inhibition ▸ nNOS inhibitor
Immunology ▸ Innate immune defense ▸ Host defense peptide ▸ Defense peptide
Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic
Standard
25 amino acids
C108H189N31O34
Standard
Sequence
GLVSSIGRALGGLLADVVKSKEQPA
Physicochemical Analysis
2465.84 Da
8.59
0.76
0.55
0.0305
0.37
0.57
0.17
40.80
124.80
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1045.25
-11.57
36.0
35.0
84.0
173.0
1.0
25.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0156044 VERIFIED: YES
Provenance & Taxonomy
Litoria splendida [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
P.haemolytica
>100 μg/mL
MIC
PaperPeptides from Australian frogs. The structures of the caerins from Litoria caerula.
RECORD: Rec_0158630 VERIFIED: YES
Provenance & Taxonomy
Litoria splendida [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Pasteurella multocida
>100 μg/mL
MIC
PaperPeptides from Australian frogs. The structures of the caerins from Litoria caerula.
RECORD: Rec_0163081 VERIFIED: NO
Provenance & Taxonomy
Magnificent tree [Animal]; Centralian tree [Animal]
Caerin
33208; 33208
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0205916 VERIFIED: NO
Provenance & Taxonomy
Ranoidea gilleni [Animal]
Caerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Amphibian defense peptide Antibiotic Antimicrobial Non-hemolytic Non-ribosomal
Qualitative functional evidence
Evidence URLhttps://www.uniprot.org/uniprotkb/P62570/entry; https://bblserver.org.in/ampdb/
RECORD: Rec_0220853 VERIFIED: NO
Provenance & Taxonomy
Ranoidea caerulea [Animal]
Caerin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Amphibian defense peptide Antibiotic Antimicrobial Non-hemolytic Non-ribosomal
Qualitative functional evidence
Evidence URLhttps://www.uniprot.org/uniprotkb/P62571/entry; https://bblserver.org.in/ampdb/
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