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MYP_042079
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Basic Information
Calcitonin
Cardiovascular
Cardiovascular ▸ Vascular tone modulation ▸ Vasoactive peptide
Cardiovascular ▸ Vascular tone modulation ▸ Vasodilatory activity
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Hormonal / Endocrine ▸ Hormone peptide
Immunology ▸ Immune modulation ▸ Immunomodulatory activity
Metabolic ▸ Appetite and feeding regulation ▸ Feeding regulator
Neurological / Signaling ▸ Analgesic/opioid activity ▸ Analgesic
Neurological / Signaling ▸ Neuromodulation
Neurological / Signaling ▸ Neuromuscular and muscle activity ▸ Myotropic activity
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide
Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide signaling
Neurological / Signaling ▸ Pain modulation ▸ Pronociceptive activity
Regulatory peptide ▸ Biological modulation
Regulatory peptide ▸ Biological regulation
Regulatory peptide ▸ Cell-cell communication
Regulatory peptide ▸ Cell signaling / Growth factor signaling ▸ Growth factor activity
Standard
32 amino acids
C151H227N39O46S3
Standard
Sequence
CGNLSTCMLGTYTQDFNKFHTFPQTAIGVGAP
Physicochemical Analysis
3420.85 Da
6.72
-0.17
-0.46
-0.0054
0.01
0.48
0.20
34.87
51.88
0.1250
1490.00
1615.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1353.81
-16.16
47.0
50.0
105.0
239.0
7.0
35.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0020110 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Calcitonin
9606
Structure & Mods
disulfide-constrained peptide [Cyclic]
canonical L-amino-acid peptide [L]
Amidation
1-7
Bio-Activity Profile
Analgesic Pronociceptive Hormone Endocrine Neuropeptide Neuromodulator Vasoactive Vasodilator Cardiovascular Metabolic regulation Physiological regulation Growth regulation Development regulation Myotropic Receptor modulation Immunomodulatory ACE inhibitory Feeding regulator
Mammalian: 1.2 hour; Yeast: >20 hour; E. coli: >10 hour
PaperSource-linked PubMed record(s) for Calcitonin (Homo sapiens): PMID 5760861 PMID5760861 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/5760861/
RECORD: Rec_0028980 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Calcitonin
9606
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Amidation
1月7日
Bio-Activity Profile
Anti-resorptive Bone metabolism
Calcitonin receptor
Clinical/Human: 10.2-37.8 min
Evidence URLhttps://www.ema.europa.eu/en/documents/referral/calcitonins-article-31-referral-annex-iii_en.pdf
RECORD: Rec_0114132 VERIFIED: YES
Provenance & Taxonomy
Homo sapiens [Animal]
Calcitonin
9606
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Amidation
1-7
Bio-Activity Profile
Hormone Calcium-regulatory peptide
PMID5760861 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/5760861/
RECORD: Rec_0145890 VERIFIED: NO
Provenance & Taxonomy
Homo sapiens [Animal]
Calcitonin
9606
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
Amidation
1-7
Bio-Activity Profile
Hormone
RECORD: Rec_0261054 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Cell-Cell Communication
PaperNeuroPedia: neuropeptide database and spectral library PMID21821666 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21821666/
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