Peptide Database

Peptide NamePyosin cloacin_T_dom domain-containing protein

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length460 amino acids

Chemical FormulaC2227H3487N619O696S11

DescriptionStandard

        MSHGQEKAGMTQILGTGEGKTSSVAKEPVVERKPAQVFFESMALAASMSGYYAGPTATTLGNSLSLGAGTAAGVGEGVAGARVLAAPNPLTVALLAIFYSPSLNEGETEMLQNIRGDQLYQNLIHSQMMVGAFTRVNSTVIQGDYVPEYELREIARQNGTVHTRVRFRIEEDPESGELVSRSYEVGEKSGLDRVRVRFAKQLNKETWGFEDPSIKGTFVWSRSAGQGKFEWGSSQTTVHDGGAGGSTTPPTPIPEPRSVWGLPNPAPASLPPVPGTPIPEEQGPNIETLPIEDRDFNDFIIVDPMGGVPAIYVYFKKAPAGFLETGYYNDFDGRSREGMYEVDHLPSKAAVREYLINKYPEAEKDDIKKLLGKVAVVSIPIDVHRDCSETFRGRNNSRIETENGETISKKELDARDLEFAVDSNWNANAKCLKERYGISDEKIEEVRAKLHDLNRRVGLY
    

Molecular Weight50420.95 Da

Isoelectric Point (pI)5.25

Net Charge (pH 7.0)-12.81

Net Charge (pH 7.4) -13.55

Charge Density (pH 7.0) -0.0278

GRAVY Index-0.47

Hydrophobic Moment 0.71

Boman Index-0.02

Instability Index42.13

Aliphatic Index 75.04

Aromaticity 0.0804

Extinction Coeff. Reduced 51340.00

Extinction Coeff. Oxidized 51465.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0175584 VERIFIED: YES

Provenance & Taxonomy

OrganismKlebsiella pneumoniae subsp. pneumoniae [Bacterium]

FamilyPyocin/Colicin

Tax ID72407

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Bacteriocin Anti-Gram-negative Non-hemolytic Non-ribosomal

TargetEscherichia coli