Peptide Database

Peptide NameBactericidal permeability-increasing protein (BPI)

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Venom / Toxin ▸ General toxin ▸ Cytotoxin

Standard StatusStandard

Sequence Length573 amino acids

Chemical FormulaC2824H4483N799O774S27

DescriptionStandard

        MCSAPAARTCRCPGVSGSLPARVHLLSGATLGMWLCLLLLMAACVPTSTSSPGIKGRVTRSALEYGRRFGLDLLRSLLQKEHDVNLQGSYRAPFLGRLNYTVPQIHIHELQMNDSTVDFAEDVGVQLTVDRARIQLSATWRAQLGAWQDSGSLQLRIRDLAVAVLLGLGADEQGQPSMWAAGCDARGTDLRLEFHQGQSWLYNLLVPLLQRTLRQQLNKQLCVEIQKGIGRLQDSLKNVRVSAQLDAFAAIDLSLLGQPGITKQHGDVDLKGEFFGVRGQWQSPFSAQPVELPELQEPMLLVAVTEFVANTAAFVYFTAGALRRNITAEMLPRRFPLKLNTESMGNFAPQLQQHFPSRPVELHLWARRQPLLSCHPNALHGAFFGSAEAFVVLPNATRVPAFLLNIDANVTGKPTIAGNRLGGTVGLKSLNVMQVMSYVGPLQVEKLENMLKFGLWLFGVPWANKRLHPGIPLPTPHGITLLHPRLSLHKVGAFPVPSPLPLCHHALLLPLSPRRASCSSPQTCSTSLETRTCVGRCWHCMLYCIPIPAPIPLASRALAASAEQWVLYPIGWD
    

Molecular Weight62877.45 Da

Isoelectric Point (pI)9.25

Net Charge (pH 7.0)14.89

Net Charge (pH 7.4) 13.52

Charge Density (pH 7.0) 0.0260

GRAVY Index0.06

Hydrophobic Moment 0.79

Boman Index0.10

Instability Index51.66

Aliphatic Index 99.77

Aromaticity 0.0716

Extinction Coeff. Reduced 77920.00

Extinction Coeff. Oxidized 78795.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0069090 VERIFIED: NO

Provenance & Taxonomy

OrganismMeleagris gallopavo [Animal]

FamilyBPI

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxin

TargetGram-negative bacteria