Peptide Database

Peptide NameHepcidin

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Standard StatusStandard

Sequence Length88 amino acids

Chemical FormulaC422H665N119O122S13

DescriptionStandard

        MKAFSVAVAVVVVLACMCIIESTAVPFSEVRTEEVGSIDSPVGEHQQPGSESMRPPELFRFKRQSHLSLCRWCCNCCHNKSCGFCCKF
    

Molecular Weight9774.36 Da

Isoelectric Point (pI)7.51

Net Charge (pH 7.0)0.68

Net Charge (pH 7.4) 0.15

Charge Density (pH 7.0) 0.0077

GRAVY Index0.16

Hydrophobic Moment 0.49

Boman Index0.06

Instability Index86.35

Aliphatic Index 69.66

Aromaticity 0.0795

Extinction Coeff. Reduced 5500.00

Extinction Coeff. Oxidized 6125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 3823.09

LogP -40.16

H-bond Donors 142.0

H-bond Acceptors 139.0

Rotatable Bonds 317.0

Heavy Atoms 676.0

Ring Count 16.0

Amide Bonds 92.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0004536 VERIFIED: NO

Provenance & Taxonomy

OrganismCoregonus ussuriensis [Animal]

FamilyHepcidin

Tax ID340692

Structure & Mods

Configgene-encoded linear polypeptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Non-hemolytic Non-ribosomal