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MYP_042008
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Basic Information
NRC-16
Anticancer
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Antimicrobial ▸ Anti-biofilm ▸ Biofilm inhibition
Antimicrobial ▸ Antifungal
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
19 amino acids
C102H166N32O21
Standard
Sequence
GWKKWLRKGAKHLGQAAIK
Physicochemical Analysis
2176.61 Da
11.39
5.84
5.58
0.3075
-0.85
0.78
-0.15
19.19
77.37
0.1053
11000.00
11000.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
882.47
-5.20
32.0
28.0
76.0
155.0
5.0
19.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0342468 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Anticancer
Human erythrocytes
256 μg/mL
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/21729875/ PMID21729875 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21729875/
RECORD: Rec_0347114 VERIFIED: YES
Provenance & Taxonomy
Actinopterygii [Animal]
7898;0
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Amidation
Bio-Activity Profile
Antibiofilm Antibacterial
Pseudomonas aeruginosa
8, 16 μM
Crystal violet assay
RECORD: Rec_0352392 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Evidence URLhttps://patents.google.com/patent/US20060093596A1/en PatentUS 2006/0093596 A1
RECORD: Rec_0355364 VERIFIED: YES
Provenance & Taxonomy
Glyptocephalus cynoglossus [Animal]
Structure & Mods
topology not specified [Not included yet]
stereochemistry not specified [Other]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Anti-Gram-negative Antifungal
Escherichia coli UB1005
2 μg/mL
MIC
PaperNovel antimicrobial peptides derived from flatfish genes. Antimicrob Agents Chemother. 2003 Aug;47(8):2464-70. doi: 10.1128/AAC.47.8.2464-2470.2003. PMID: 12878506. PMID12878506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12878506/
RECORD: Rec_0361082 VERIFIED: YES
Provenance & Taxonomy
Glyptocephalus cynoglossus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antifungal
Escherichia coli CGSC4908
1 μM
MIC
PaperNovel antimicrobial peptides derived from flatfish genes PMID12878506 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/12878506/
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