Peptide Database

Peptide NameTP10

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral replication inhibition

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length14 amino acids

Chemical FormulaC86H137N25O20S2

DescriptionStandard

        QMRRKVELFTYMRF
    

Molecular Weight1905.29 Da

Isoelectric Point (pI)10.90

Net Charge (pH 7.0)2.76

Net Charge (pH 7.4) 2.55

Charge Density (pH 7.0) 0.1972

GRAVY Index-0.64

Hydrophobic Moment 0.45

Boman Index-0.33

Instability Index64.75

Aliphatic Index 48.57

Aromaticity 0.2143

Extinction Coeff. Reduced 1490.00

Extinction Coeff. Oxidized 1490.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 774.19

LogP -4.23

H-bond Donors 29.0

H-bond Acceptors 25.0

Rotatable Bonds 65.0

Heavy Atoms 133.0

Ring Count 3.0

Amide Bonds 14.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0077555 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAcetylation

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antiviral Cytotoxic

RECORD: Rec_0148785 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAcetylation

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antiviral

TargetEnterovirus A71 (EV-A71):inhibition of viral replication into RD cells

Activity6.7 μM

MethodIC50

RECORD: Rec_0181256 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAcetylation

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antiviral

RECORD: Rec_0233992 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAcetylation

C-TermAmidation

Bio-Activity Profile

Function

Antimicrobial Antiviral Cytotoxic

TargetRD cells

Activity231 μM

MethodCC50

RECORD: Rec_0280969 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilySynthetic peptide

Tax ID32630

Structure & Mods

Configsynthetic linear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAcetylation

C-TermAmidation

Other ModsFree

Bio-Activity Profile

Function

Antiviral Replication inhibition

TargetEnterovirus A71 (EV-A71) | RD cells

Activity6.7 μM

MethodIC50

Half-LifeMammalian: 0.8 h; Yeast: 10 min; E. coli: >10 h