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MYP_041988
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Basic Information
PVEC [I9W,K11R,H14R,H16R,K18R]
Antimicrobial
Antimicrobial ▸ Antibacterial
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Venom / Toxin ▸ General toxin ▸ Toxic
Standard
18 amino acids
C103H186N44O21
Standard
Sequence
LLIILRRRWRRQARARSR
Physicochemical Analysis
2376.86 Da
12.00
7.76
7.56
0.4311
-0.96
0.78
-0.74
203.94
119.44
0.0556
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1132.33
-10.00
46.0
29.0
83.0
168.0
2.0
18.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0084437 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Salmonella typhimurium KCTC 1926
4 μM
MIC
PMID21956793 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21956793/
RECORD: Rec_0100777 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide; DSSP H 61.1%, E 0.0%, T 11.1%, C 27.8% [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Toxic Antimicrobial Drug Delivery Vehicle Cell-penetrating peptide Hemolytic
PaperHemolytik: a database of experimentally determined hemolytic and non-hemolytic peptides PMID24174543 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/24174543/
RECORD: Rec_0112034 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Staphylococcus aureus KCTC 1621
4 μM
MIC
PMID21956793 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21956793/
RECORD: Rec_0113068 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial
Escherichia coli KCTC 1682
8 μM
MIC
PMID21956793 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21956793/
RECORD: Rec_0146620 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
Amidation
Bio-Activity Profile
Antimicrobial Cell-penetrating peptide
Human erythrocytes
94 μM
Hemolysis
Paperhttps://pubmed.ncbi.nlm.nih.gov/21956793/ PMID21956793 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21956793/
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