Peptide Database

Peptide NameCyclotide psyle B

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length28 amino acids

Chemical FormulaC132H195N31O39S6

DescriptionStandard

        GIPCGETCVAFGCWIPGCSCKDKLCYYD
    

Molecular Weight3032.53 Da

Isoelectric Point (pI)4.78

Net Charge (pH 7.0)-1.30

Net Charge (pH 7.4) -1.60

Charge Density (pH 7.0) -0.0463

GRAVY Index0.30

Hydrophobic Moment 0.20

Boman Index0.22

Instability Index23.38

Aliphatic Index 55.71

Aromaticity 0.1429

Extinction Coeff. Reduced 8480.00

Extinction Coeff. Oxidized 8855.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1092.09

LogP -9.27

H-bond Donors 43.0

H-bond Acceptors 44.0

Rotatable Bonds 91.0

Heavy Atoms 208.0

Ring Count 7.0

Amide Bonds 27.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0155958 VERIFIED: NO

Provenance & Taxonomy

OrganismPsychotria leptothyrsa [Plant]

FamilyCyclotide

Structure & Mods

Confighead-to-tail cyclic peptide [Cyclic]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Cytotoxic

RECORD: Rec_0405311 VERIFIED: YES