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MYP_041972
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Basic Information
Defensin def2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
37 amino acids
C188H279N55O46S6
Standard
Sequence
GGYYCPFFQDKCHRHCRSFGRKAGYCGGFLKKTCICV
Physicochemical Analysis
4237.96 Da
9.27
5.87
5.47
0.1586
-0.31
0.80
-0.05
50.03
31.62
0.1892
4470.00
4845.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1630.81
-15.34
65.0
60.0
136.0
295.0
10.0
37.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0282974 VERIFIED: YES
Provenance & Taxonomy
European tick [Animal]
Defensin
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
Staphylococcus xylosus, Micrococcus luteus, Bacillus subtilis, MRSA
PaperFunctional characterization of two defensin isoforms of the hard tick Ixodes ricinus
RECORD: Rec_0292530 VERIFIED: NO
Provenance & Taxonomy
European tick [Animal]; Arthropoda [Animal]
33208; 6656
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial
RECORD: Rec_0320171 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Plant]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
5-26, 12-34, 16-36
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Staphylococcus aureus (MRSA)
50 μM
MIC
PMID21504572 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21504572/
RECORD: Rec_0359745 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Plant]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
5-26, 12-34, 16-36
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Micrococcus luteus
0.75 μM
MIC
PMID21504572 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21504572/
RECORD: Rec_0369708 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
MS-1
2 μg/mL
MIC
PMID27531221 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/27531221/
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