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MYP_041972
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Basic Information
Defensin def2
Antimicrobial
Antimicrobial ▸ Antibacterial
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative
Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Standard
37 amino acids
C188H279N55O46S6
Standard
Sequence
GGYYCPFFQDKCHRHCRSFGRKAGYCGGFLKKTCICV
Physicochemical Analysis
4237.96 Da
9.27
5.87
5.47
0.1586
-0.31
0.80
-0.05
50.03
31.62
0.1892
4470.00
4845.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
1630.81
-15.34
65.0
60.0
136.0
295.0
10.0
37.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0172560 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Plant]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
5-26, 12-34, 16-36
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Hemolytic
PMID21504572 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21504572/
RECORD: Rec_0178785 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Plant]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
5-26, 12-34, 16-36
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive Hemolytic
human erythrocytes
PMID21504572 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21504572/
RECORD: Rec_0197789 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Plant]
Defensin
Structure & Mods
disulfide-constrained cyclic peptide [Cyclic]
canonical L-amino-acid peptide [L]
None
None
5-26, 12-34, 16-36
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Bacillus subtilis
1.5 μM
MIC
PMID21504572 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21504572/
RECORD: Rec_0242101 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Animal]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Bacillus subtilis
1.5 μM
MIC
PMID21504572 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21504572/
RECORD: Rec_0277997 VERIFIED: YES
Provenance & Taxonomy
Ixodes ricinus [Animal]
Defensin
Structure & Mods
Single-chain peptide backbone represented as a linear sequence entry [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antimicrobial Antibacterial Anti-Gram-positive
Micrococcus luteus
0.75 μM
MIC
PMID21504572 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/21504572/
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