Peptide Database

Peptide NameTWEAK

Function Ontology

Neurological / Signaling ▸ Signaling peptide

Standard StatusStandard

Sequence Length249 amino acids

Chemical FormulaC1205H1943N361O348S5

DescriptionStandard

        MAARRSQRRRGRRGEPGTALLVPLALGLGLALACLGLLLAVVSLGSRASLSAQEPAQEELVAEEDQDPSELNPQTEESQDPAPFLNRLVRPRRSAPKGRKTRARRAIAAHYEVHPRPGQDGAQAGVDGTVSGWEEARINSSSPLRYNRQIGEFIVTRAGLYYLYCQVHFDEGKAVYLKLDLLVDGVLALRCLEEFSATAASSLGPQLRLCQVSGLLALRPGSSLRIRTLPWAHLKAAPFLTYFGLFQVH
    

Molecular Weight27215.85 Da

Isoelectric Point (pI)9.50

Net Charge (pH 7.0)6.94

Net Charge (pH 7.4) 6.36

Charge Density (pH 7.0) 0.0279

GRAVY Index-0.18

Hydrophobic Moment 0.71

Boman Index-0.02

Instability Index61.85

Aliphatic Index 96.87

Aromaticity 0.0643

Extinction Coeff. Reduced 21430.00

Extinction Coeff. Oxidized 21680.00

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Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0194694 VERIFIED: NO

Provenance & Taxonomy

OrganismHomo sapiens [Animal]

FamilyGtoPdb endogenous peptide ligand

Tax ID9606

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Signaling peptide

TargetTWEAK receptor (Human)