Peptide Database

Peptide NameSLAY-screened peptide P3084

Function Ontology

Antimicrobial

Antimicrobial ▸ Antibacterial

Standard StatusStandard

Sequence Length20 amino acids

Chemical FormulaC101H155N27O33S

DescriptionStandard

        PYSPCDYTTTLSRVNSSFIR
    

Molecular Weight2307.54 Da

Isoelectric Point (pI)8.60

Net Charge (pH 7.0)0.95

Net Charge (pH 7.4) 0.87

Charge Density (pH 7.0) 0.0474

GRAVY Index-0.47

Hydrophobic Moment 0.69

Boman Index-0.09

Instability Index52.34

Aliphatic Index 53.50

Aromaticity 0.1500

Extinction Coeff. Reduced 2980.00

Extinction Coeff. Oxidized 2980.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 979.70

LogP -12.65

H-bond Donors 38.0

H-bond Acceptors 35.0

Rotatable Bonds 69.0

Heavy Atoms 162.0

Ring Count 5.0

Amide Bonds 20.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0132769 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitystereochemistry not specified [Other]

Bio-Activity Profile

Function

Antimicrobial Antibacterial

Targetrecombinant Escherichia coli surface-display screening

MethodSLAY screening

PaperAshley T Tucker, Sean P Leonard, Cory D DuBois, Gregory A Knauf, Ashley L Cunningham, Claus O Wilke, M Stephen Trent, Bryan W Davies. Discovery of Next-Generation Antimicrobials through Bacterial Self-Screening of Surface-Displayed Peptide Libraries. Cell. 2018 Jan 25;172(3):618-628.e13. doi: 10.1016/j.cell.2017.12.009. Epub 2018 Jan 4. PMID29307492 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/29307492/