Peptide Database

Peptide NameFMRFamide-related protein 1

Function Ontology

Neurological / Signaling ▸ Neuromodulation

Neurological / Signaling ▸ Neuropeptide activity ▸ Neuropeptide

Standard StatusStandard

Sequence Length8 amino acids

Chemical FormulaC47H71N13O12

DescriptionStandard

        AKDNFLRF
    

Molecular Weight1010.15 Da

Isoelectric Point (pI)8.79

Net Charge (pH 7.0)0.80

Net Charge (pH 7.4) 0.61

Charge Density (pH 7.0) 0.0995

GRAVY Index-0.53

Hydrophobic Moment 0.59

Boman Index-0.21

Instability Index14.04

Aliphatic Index 61.25

Aromaticity 0.2500

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 435.33

LogP -2.91

H-bond Donors 15.0

H-bond Acceptors 13.0

Rotatable Bonds 33.0

Heavy Atoms 72.0

Ring Count 2.0

Amide Bonds 8.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0055750 VERIFIED: YES

Provenance & Taxonomy

OrganismRhodnius prolixus [Animal]

FamilyFMRFamide-related protein

Tax ID13249

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAcetylation

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide Neuromodulator

Half-LifeMammalian: 4.4 hour; Yeast: >20 hour; E. coli: >10 hour

RECORD: Rec_0116793 VERIFIED: YES

Provenance & Taxonomy

OrganismRhodnius prolixus [Animal]

FamilyFMRFamide related peptide

Tax ID13249

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermAcetylation

C-TermAmidation

Bio-Activity Profile

Function

RFamide Neuropeptide Neuromodulator

RECORD: Rec_0164210 VERIFIED: YES

Provenance & Taxonomy

Organismnot reported [other]

FamilyFMRFamide-like peptide

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide

Paper数据库级溯源文献：Wang Y, Wang M, Yin S, et al. NeuroPep: a comprehensive resource of neuropeptides. Database (Oxford). 2015:bav038. PMID 25931458; Bin Y, Zhang W, Tang W, et al. Prediction of Neuropeptides from Sequence Information Using Ensemble Classifier and Hybrid Features. J Proteome Res. 2020;19(9):3732-3740. PMID 32786686. PMID25931458;32786686 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/25931458/

RECORD: Rec_0281510 VERIFIED: NO

Provenance & Taxonomy

OrganismRhodnius prolixus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermBlocked

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide

RECORD: Rec_0294174 VERIFIED: NO

Provenance & Taxonomy

OrganismRhodnius prolixus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

C-TermAmidation

Bio-Activity Profile

Function

Neuropeptide