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MYP_041928
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Basic Information
GBV-A10 [Y8E]
Antimicrobial
Antiviral
Antiviral ▸ Anti-Hepatitis virus ▸ Anti-HCV
Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition
Standard
18 amino acids
C102H170N32O23S
Standard
Sequence
CWVRLGRELLRRLKTPFT
Physicochemical Analysis
2244.71 Da
11.54
3.75
3.53
0.2084
-0.28
0.97
-0.24
66.39
102.78
0.1111
5500.00
5500.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
916.40
-5.68
36.0
28.0
73.0
158.0
4.0
17.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0365070 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
Protein-derived synthetic peptide
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
None
None
Bio-Activity Profile
Antiviral Anti-HCV Entry inhibition
Hepatitis C virus(Jc1-Luc HCVcc) | Huh7.5.1 cells
20 μM
IC50
Mammalian: 1.2 h; Yeast: >20 h; E. coli: >10 h
PaperScreening and rational design of hepatitis C virus entry inhibitory peptides derived from GB virus A NS5A. | Liu X, Huang Y, Cheng M, Pan L, Si Y, Li G, Niu Y, Zhao L, Zhao J, Li X, Chen Y, Yang W. | J Virol. 2013 Feb;87(3):1649-57. | DOI:10.1128/JVI.02201-12 | PMID:23175359 PMID23175359 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23175359/
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