Peptide Database

Peptide NameBrevinin-2TP1

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-positive

Antimicrobial ▸ Antifungal

Membrane / Ion-channel modulation ▸ Calcium channel modulation ▸ Calcium channel inhibitor

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Toxic

Standard StatusStandard

Sequence Length33 amino acids

Chemical FormulaC144H257N39O46S2

DescriptionStandard

        SILSTLKDVGISAIKSAGSGVLSTLLCKLNKNC
    

Molecular Weight3334.94 Da

Isoelectric Point (pI)9.30

Net Charge (pH 7.0)2.44

Net Charge (pH 7.4) 2.19

Charge Density (pH 7.0) 0.0739

GRAVY Index0.60

Hydrophobic Moment 0.48

Boman Index0.19

Instability Index8.97

Aliphatic Index 130.00

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 125.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 1383.92

LogP -17.11

H-bond Donors 51.0

H-bond Acceptors 51.0

Rotatable Bonds 117.0

Heavy Atoms 231.0

Ring Count 0.0

Amide Bonds 34.0

3D PDB MODEL

Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber in the current view mode. Use the buttons to zoom.

2D CHEMICAL STRUCTURE

Drag to move

Drag to move. Use the buttons to zoom.

RECORD: Rec_0392557 VERIFIED: YES

Provenance & Taxonomy

OrganismHylarana taipehensis [Animal]

FamilyBrevinin

Tax ID110118

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Disulfide27-33

Bio-Activity Profile

Function

Antimicrobial Antioxidant

TargetP. faecalis X29

Activity6.3 μM

MethodMIC

RECORD: Rec_0407224 VERIFIED: YES