Peptide Database

Peptide NameBactericidal permeability-increasing protein

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antimicrobial ▸ Antibacterial ▸ Anti-Gram-negative

Antimicrobial ▸ Antibiotic activity

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Toxicity / Safety ▸ Negative safety assay result ▸ Non-hemolytic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length264 amino acids

Chemical FormulaC1347H2101N343O391S6

DescriptionStandard

        MEKPILKNLNEMLCPIITGEVEALNANLSALEVLRKIDNYTLLDYSLIDSPEVTENYLDLNLKGVFYPLENLADPPFSPVPFMLPERSDSMLYIGISEYFFKSASFAYFTAGAFDVTLSTKEISNHFIQNSQGLGNVLSRVASTSVGLVILGQRLICSLSLNRFRLSLPEPNHSNIEVLRFENILSSILHFGVLPLANAKLQQGFPLPNPHKISFVNSDIEVLEGFLLISTDLNYETSSKRQPSFHGWEGLNLISRQWRGKPAP
    

Molecular Weight29548.54 Da

Isoelectric Point (pI)5.28

Net Charge (pH 7.0)-7.04

Net Charge (pH 7.4) -7.60

Charge Density (pH 7.0) -0.0267

GRAVY Index0.02

Hydrophobic Moment 0.72

Boman Index0.13

Instability Index46.66

Aliphatic Index 105.61

Aromaticity 0.0985

Extinction Coeff. Reduced 22920.00

Extinction Coeff. Oxidized 23045.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0203578 VERIFIED: NO

Provenance & Taxonomy

OrganismProlemur simus [Animal]

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

Bio-Activity Profile

Function

Antibiotic Antimicrobial Anti-Gram-negative Cytotoxic Non-hemolytic Non-ribosomal

TargetGram-negative bacteria

MethodQualitative functional evidence