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MYP_041857
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Basic Information
PolyP 4
Anticancer
Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic
Antimicrobial
Cardiovascular ▸ Blood pressure regulation ▸ Antihypertensive
Delivery / Targeting ▸ Cell penetration ▸ Cell-penetrating peptide
Delivery / Targeting ▸ Drug delivery vehicle
Enzyme modulation ▸ Enzyme inhibition ▸ ACE inhibition ▸ ACE inhibitory
Other / Curated residual function label ▸ Generic enzyme inhibition annotation
Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic
Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic
Venom / Toxin ▸ General toxin ▸ Cytotoxic
Standard
6 amino acids
C32H50N8O7
Standard
Sequence
VHLPPP
Physicochemical Analysis
658.79 Da
6.71
-0.18
-0.44
-0.0298
0.00
0.12
0.35
104.63
113.33
0.0000
0.00
0.00
The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.
Residue Composition
Amino Acid Composition
Chemical Descriptors
211.13
0.01
5.0
8.0
13.0
47.0
4.0
5.0
Structural Visualization
3D PDB MODEL
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2D CHEMICAL STRUCTURE
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Experimental Records
RECORD: Rec_0012736 VERIFIED: YES
Provenance & Taxonomy
not reported [other]
PolyP
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein/FITC labeling
None
Bio-Activity Profile
Cell-penetrating peptide Cargo delivery
PMID15054781 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15054781/
RECORD: Rec_0047731 VERIFIED: YES
Provenance & Taxonomy
synthetic construct [Synthetic]
32630
Structure & Mods
synthetic linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
Angiotensin-converting enzyme (ACE)
200.0
IC50
PaperMaruyama S., Miyoshi S., Kaneko T., Tanaka H.. Angotensin I-converting enzyme inhibitory activities of synthetic peptides related to the tandem repeated sequence of a maize endosperm protein.Agric.Biol.Chem.53(4),1077-1081(1989).
RECORD: Rec_0073262 VERIFIED: NO
Provenance & Taxonomy
not reported [other]
ACE-inhibitory peptide
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Bio-Activity Profile
Antihypertensive ACE inhibitory
ACE
200 μM
IC50
PaperA new QSAR model, for angiotensin I-converting enzyme inhibitory oligopeptides. PMID23194537 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/23194537/
RECORD: Rec_0095871 VERIFIED: YES
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein
None
Bio-Activity Profile
Antimicrobial Anticancer Hemolytic
PMID15054781 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15054781/
RECORD: Rec_0151933 VERIFIED: YES
Provenance & Taxonomy
Protein derived [Animal]
Structure & Mods
linear peptide [Linear]
canonical L-amino-acid peptide [L]
Fluorescein
None
Bio-Activity Profile
Antimicrobial Anticancer Cytotoxic
PMID15054781 Evidence URLhttps://pubmed.ncbi.nlm.nih.gov/15054781/
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