Peptide Database

Peptide NameAlloferon (1-11)

Function Ontology

Anticancer ▸ Cytotoxic anticancer activity ▸ Cytotoxic

Antimicrobial

Antiviral

Antiviral ▸ Antiviral mechanism ▸ Viral entry inhibition

Toxicity / Safety ▸ Blood cell toxicity ▸ Hemolysis ▸ Hemolytic

Toxicity / Safety ▸ Cytotoxicity ▸ Cytotoxic

Venom / Toxin ▸ General toxin ▸ Cytotoxic

Standard StatusStandard

Sequence Length11 amino acids

Chemical FormulaC44H66N18O14

DescriptionStandard

        HGVSGHGQHGV
    

Molecular Weight1071.11 Da

Isoelectric Point (pI)7.02

Net Charge (pH 7.0)0.02

Net Charge (pH 7.4) -0.33

Charge Density (pH 7.0) 0.0020

GRAVY Index-0.65

Hydrophobic Moment 0.24

Boman Index0.17

Instability Index-19.19

Aliphatic Index 52.73

Aromaticity 0.0000

Extinction Coeff. Reduced 0.00

Extinction Coeff. Oxidized 0.00

The radar chart summarizes major physicochemical dimensions for quick comparison, while exact numerical values remain listed on the left.

Amino Acid Composition

TPSA 503.68

LogP -7.76

H-bond Donors 17.0

H-bond Acceptors 17.0

Rotatable Bonds 33.0

Heavy Atoms 76.0

Ring Count 3.0

Amide Bonds 11.0

3D PDB MODEL

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2D CHEMICAL STRUCTURE

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RECORD: Rec_0365201 VERIFIED: YES

Provenance & Taxonomy

Organismsynthetic construct [Synthetic]

FamilyAlloferon

Tax ID32630

Structure & Mods

Configlinear peptide [Linear]

Chiralitycanonical L-amino-acid peptide [L]

N-TermNone

C-TermNone

Bio-Activity Profile

Function

Antimicrobial Antiviral Cytotoxic

Targettoxic against Vero cells up to 260 μM

Activity260 μM

MethodCytotoxicity

RECORD: Rec_0399561 VERIFIED: YES